Berberine

Discover Naturecan’s Berberine Supplement, expertly formulated to support everyday health and long-term wellbeing. Sourced from high-quality ingredients and developed with wellness at the forefront, our berberine supplement is designed to help maintain normal cholesterol levels, support healthy blood sugar regulation and overall vitality.

Supplementing with berberine offers a convenient and effective way to provide your body with essential support, helping it function efficiently and stay balanced. 

Key Benefits:

• Helps to reduce blood triglyceride levels
• Helps to maintain a normal cholesterol level
• Potentially Supports Gut Health
• Natural antioxidant
• May contribute to weight management

  Read our Certificate of Analysis (CoA)

Product Overview 

• Vegan
• 500mg per capsule
• 2 month supply

This product is made only using plant extracts and HPMC capsules, therefore, is suitable for all diets including Vegan and Vegetarian. Packed with 500mg of pure Berberine per serving, in capsule form Berberine capsules can be easily swallowed and incorporated into your daily routine for convenience. 

What Is Berberine?

Berberine is a natural compound found in several plants, including the Berberis species and has been used for centuries in traditional medicine. It’s a bitter-tasting yellow substance that is typically made in capsule or tablet form for maximum benefits, without the bitter taste. 

It works by activating an enzyme called AMP-activated protein kinase (AMPK), which helps manage energy production in cells. In addition to potential metabolic benefits, Berberine may have multiple longevity-based benefits, making it a powerful supplement for overall health.

Serving Instructions

Take one capsule daily with water, ideally alongside food. Consistency is key, aim to take it at the same time each day for best results.

Berberine can also potentially interact with certain medications, so be sure to check with a medical professional if you're on any prescribed medications. 

Pregnant or breastfeeding women are advised to avoid Berberine due to limited research on its safety during these stages. 

Ingredients

Berberine HCL, Glazing Agent (Capsule (Hydroxypropyl Methylcellulose)), Bulking Agent (Stoneground Brown Rice Flour), Anti-Caking Agent (Magnesium Stearate)

Nutritional Information:

Berberine Capsules:  1 capsule per serving - 60 servings

Certainty of Purity

When it comes to your health, purity matters. At Naturecan, each ingredient we use is tested, traceable, and trusted.

Our Promise:

• Third-party tested for purity and potency
• Made in Europe
• Sustainably sourced and vegan-friendly
• Transparent from start to shelf, you always know what’s inside

We believe in doing things properly, no shortcuts, no false promises, just clean, science-backed nutrition that works.

Is Berberine Right For You?

You will love Berberine if you’re:

• Looking to regulate your blood triglyceride levels
• Looking to maintain a normal cholesterol level
• Interested in supporting metabolic health
• Wanting to support gut health
• Focused on weight management and support
• Wanting to take a science-backed approach to wellness

It’s a great fit for anyone who wants to support a longevity focused daily wellness routine.

Key Studies

Here’s what the science says:

1. Metabolic health and lipid profiles
   A review of randomised clinical trials found that berberine may produce favourable changes in multiple metabolic markers, including reducing triglycerides, total cholesterol, LDL (“bad” cholesterol), fasting glucose, and insulin resistance. While increasing HDL (“good” cholesterol) in adults with metabolic disorders. These changes suggest a possible role for Berberine in supporting markers of cardiometabolic function and glucose regulation. [1]
2. Weight management and inflammatory biomarkers
   Evidence indicates that berberine supplementation is associated with modest reductions in body weight, body mass index (BMI), waist circumference, and inflammatory marker C-reactive protein (CRP). These effects suggest a potential use for body composition and underlying metabolic inflammation, although more research is needed. [2]
3. Mechanistic insights into weight and metabolic modulation
   Reviews of experimental and clinical evidence suggest that berberine may influence obesity-related pathways through mechanisms such as activation of AMP-activated protein kinase (AMPK), inhibition of adipocyte differentiation, and modulation of gut microbiota, mechanisms that may underline its effects on weight and metabolic outcomes. [3]
   

Can Berberine Be Taken By Everyone?

Although Berberine offers many health benefits, it may not be suitable for everyone. It is well-tolerated when taken at recommended doses, but those with existing medical conditions should consult a healthcare professional before use. 

Naturecan’s Commitment to Quality

Naturecan exist to connect nature and innovation, creating supplements that are safe, effective and backed by evidence. Every batch is tested for purity, and every ingredient has a purpose.

• Third-party verified for complete peace of mind
• Vegan and responsibly sourced
• Transparent and traceable from ingredient to finished product
  

References

1. Feng X, Sureda A, Jafari S, Memariani Z, Tewari D, Annunziata G, Barrea L, Hassan STS, Šmejkal K, Malaník M, Sychrová A, Barreca D, Ziberna L, Mahomoodally MF, Zengin G, Xu S, Nabavi SM, Shen AZ. Berberine in Cardiovascular and Metabolic Diseases. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC6485276/ 
2. Asbaghi O, Ghanbari N, Shekari M, Reiner Ž, Amirani E, Hallajzadeh J, Mirsafaei L, Asemi Z. The effect of berberine supplementation on obesity parameters, inflammation and liver function enzymes: A systematic review and meta-analysis of randomized controlled trials. Available at: https://pubmed.ncbi.nlm.nih.gov/32690176/ 
3. Xu JH, Liu XZ, Pan W, Zou DJ. Berberine protects against diet-induced obesity through regulating metabolic endotoxemia and gut hormone levels. Available at: https://pmc.ncbi.nlm.nih.gov/articles/PMC5428400/